Description

4-(Trifluoromethoxy)Benzotrifluoride is a versatile fluorinated aromatic building block characterized by its unique trifluoromethoxy and benzotrifluoride functional groups. This compound is highly valued for its ability to impart significant lipophilicity, metabolic stability, and electron-withdrawing properties to advanced molecular structures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the trifluoromethoxy group to enhance bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a fluorinated component in the synthesis of liquid crystals for display technologies, improving dielectric anisotropy and stability.
• Organic Electronics: Employed as a building block for electron-transport materials and semiconductors in OLEDs and other electronic devices.
• Advanced Polymer Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A valuable reagent in organic synthesis for exploring new fluorination methodologies and creating complex fluorinated architectures.

Basic Information

Product Name	4-(Trifluoromethoxy)Benzotrifluoride
CAS No.	80258-33-9
Molecular Formula	C8H4F6O
Molecular Weight	230.11 g/mol
Synonyms	1-(Trifluoromethoxy)-4-(trifluoromethyl)benzene; α,α,α-Trifluoro-4-(trifluoromethoxy)toluene; p-(Trifluoromethoxy)benzotrifluoride; 4-(Trifluoromethoxy)benzotrifluoride; 4-(Trifluoromethoxy)-α,α,α-trifluorotoluene; 1-Trifluoromethoxy-4-trifluoromethyl-benzene; (Trifluoromethoxy)benzotrifluoride
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Benzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are securely sealed when not in use. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.