Description

H-Tyr-Gly-Gly-Phe-Met-Lys-Lys-OH is a synthetic heptapeptide with the sequence Tyr-Gly-Gly-Phe-Met-Lys-Lys, representing a modified fragment of the endogenous opioid peptide, Met-enkephalin. This compound is of significant interest for research into opioid receptor interactions and peptide-based drug discovery. It serves as a critical biochemical tool for pharmaceutical R&D, academic research, and biotechnology applications focused on neurobiology, pain management, and peptide chemistry.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of opioid receptor binding, signaling pathways, and structure-activity relationships (SAR).
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the discovery and development of novel analgesic and neuropharmacological agents.
• Academic Studies: Employed in university and institutional labs for teaching and investigating peptide synthesis, modification, and biological evaluation techniques.
• Biotechnology: Utilized in assay development, high-throughput screening (HTS) platforms, and as a calibrant in analytical method development for peptide quantification.

Basic Information

Product Name	H-Tyr-Gly-Gly-Phe-Met-Lys-Lys-OH
CAS No.	80237-40-7
Molecular Formula	C41H62N10O10S
Molecular Weight	887.06 g/mol
Synonyms	Tyr-Gly-Gly-Phe-Met-Lys-Lys; YGGFMKK; H-Tyr-Gly-Gly-Phe-Met-Lys-Lys; Enkephalin, Met- (6-7)-Lys-Lys; Heptapeptide YGGFMKK; Opioid peptide fragment YGGFMKK; L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-lysyl-L-lysine
EINECS	Contact for details

Quality Control

Our H-Tyr-Gly-Gly-Phe-Met-Lys-Lys-OH is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.