Description

Acth (1-26), Cys-Carboxamidomethyl(25)- CAS NO 80154-41-2 is a synthetic peptide fragment of the adrenocorticotropic hormone (ACTH), specifically modified at the cysteine residue. This compound is of significant value for biochemical research and pharmaceutical development due to its role in studying the structure-activity relationships of ACTH and its receptor interactions. It is primarily needed by research institutions, biotechnology companies, and pharmaceutical developers focused on endocrinology, peptide-based therapeutics, and diagnostic assay development.

Application

• Biochemical Research: Used as a reference standard and active agent in studies investigating the physiological functions and signaling pathways of ACTH.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of peptide-based therapeutics targeting adrenal function.
• Diagnostic Reagents: Employed in the formulation of immunoassays and diagnostic kits for measuring ACTH levels in clinical and research settings.
• Receptor Binding Studies: Essential for in vitro assays to characterize binding affinity and specificity to melanocortin receptors (MC2R).
• Academic Research: Utilized in university and institutional labs for teaching and advanced research in peptide chemistry and endocrinology.

Basic Information

Product Name	Acth (1-26), Cys-Carboxamidomethyl(25)- CAS NO 80154-41-2
CAS No.	80154-41-2
Molecular Formula	C₁₄₆H₂₃₈N₄₄O₄₃S₂
Molecular Weight	~3400 g/mol (monoisotopic)
Synonyms	ACTH (1-26), Cys(25)-Carboxamidomethyl; Adrenocorticotropic Hormone Fragment 1-26, Cys-Cam(25); [Cys(Cam)²⁵]-ACTH (1-26); Corticotropin (1-26), S-[2-[(Aminocarbonyl)methyl]thio]-25-L-cysteine-; Cosyntropin derivative; Norleusactide derivative; Tetracosactide hexaacetate related peptide; 80154-41-2
EINECS	Contact for details

Quality Control

Our Acth (1-26), Cys-Carboxamidomethyl(25)- CAS NO 80154-41-2 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting high standards for research and development use. Certificates of Analysis (COA) providing detailed results for purity, related substances, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature, ideally between 15-25°C, in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture. For long-term stability, consider storage at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.