Description

5-Fluoro-2-Methylbenzyl Cyanide is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a reactive benzylic nitrile group and a fluorine substituent, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity, stability, and metabolic profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic materials, contributing to improved dielectric anisotropy and performance in display technologies.
• Advanced Polymer Chemistry: Incorporated into specialty polymer chains to modify thermal stability, chemical resistance, and optical properties of high-performance resins.
• Organic Synthesis & Research: A valuable reagent for introducing the 5-fluoro-2-methylbenzyl moiety into more complex molecular architectures via reactions at the cyano group.

Basic Information

Product Name	5-Fluoro-2-Methylbenzyl Cyanide
CAS No.	80141-97-5
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	(5-Fluoro-2-methylphenyl)acetonitrile; 2-(5-Fluoro-2-methylphenyl)acetonitrile; 5-Fluoro-2-methylbenzeneacetonitrile; 5-Fluoro-α-tolunitrile; 5-Fluoro-o-methylbenzyl cyanide; α-Cyano-5-fluoro-2-methyltoluene; 80141-97-5
EINECS	Contact for details

Quality Control

Our production of 5-Fluoro-2-Methylbenzyl Cyanide adheres to stringent quality management protocols. Each batch is analytically verified using advanced techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.