Description

Clofibric Furanoglucuronate is a specific metabolite and analytical reference standard of the lipid-regulating agent clofibrate. This compound is of significant value in pharmaceutical research and development, particularly for metabolic and pharmacokinetic studies. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies involved in drug metabolism, bioanalytical method development, and quality control of related pharmaceutical products.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the quantification and identification of clofibrate metabolites in biological matrices.
• Metabolite Research: Critical for studying the metabolic pathways, pharmacokinetics, and excretion profiles of clofibrate and related fibrate drugs.
• Bioanalytical Method Development: Used as a standard in developing and validating HPLC, LC-MS, and GC-MS methods for drug metabolism and pharmacokinetic (DMPK) studies.
• Impurity Profiling: Employed in the identification and control of process-related impurities or degradation products in clofibrate API manufacturing.
• Toxicological Studies: Applied in research investigating the long-term effects and safety profile of clofibrate metabolites.

Basic Information

Product Name	Clofibric Furanoglucuronate
CAS No.	80106-54-3
Molecular Formula	C19H22O10
Molecular Weight	410.37 g/mol
Synonyms	Clofibrate Glucuronide; Clofibric Acid Glucuronide; 1-O-[2-(4-Chlorophenoxy)-2-methylpropanoyl]-β-D-glucopyranuronic Acid; 2-(4-Chlorophenoxy)-2-methylpropanoic Acid 1-β-D-Glucopyranuronosyl Ester; CPIB-Glucuronide; Clofibrate Metabolite Glucuronide
EINECS	Contact for details

Quality Control

Our Clofibric Furanoglucuronate is manufactured and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.