Description

H-Glu(Obzl)-Nh2 Hcl is a protected glutamic acid derivative, specifically the benzyl ester hydrochloride salt of glutamine. This compound serves as a crucial building block (amino acid derivative) in the synthesis of complex peptides and pharmaceutical intermediates. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Peptide Synthesis: A key protected amino acid precursor in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediate: Used in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Serves as a reagent for studying enzyme-substrate interactions and metabolic pathways involving glutamic acid or glutamine.
• Protecting Group Chemistry: The Obzl (benzyl ester) group provides a standard protecting strategy for the γ-carboxyl side chain of glutamic acid during multi-step syntheses.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and complex organic molecules for various industrial applications.

Basic Information

Product Name	H-Glu(Obzl)-Nh2 Hcl
CAS No.	80064-48-8
Molecular Formula	C₁₂H₁₇ClN₂O₄
Molecular Weight	288.73 g/mol
Synonyms	L-Glutamine, N2-benzyl ester, hydrochloride; H-Gln(OBzl)-OH·HCl; Glutamine benzyl ester hydrochloride; (S)-2-Amino-4-carbamoylbutanoic acid benzyl ester hydrochloride; Benzyl L-glutaminate hydrochloride; Fmoc-Gln(OBzl)-OH (related protected form); γ-Benzyl L-glutaminate hydrochloride
EINECS	Contact for details

Quality Control

Our H-Glu(Obzl)-Nh2 Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.