Description

4-Fluoro-n-(2-Methylbut-3-Yn-2-Yl)Benzamide is a specialized fluorinated benzamide derivative featuring an alkyne functional group. This compound matters as a high-value chemical building block and pharmaceutical intermediate, enabling the synthesis of more complex molecules through its reactive sites. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in developing new generation herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Chemical Biology Probe: The alkyne moiety allows for click chemistry applications, such as bioconjugation and labeling for proteomics and diagnostic assay development.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex heterocycles and fluorinated compounds via Sonogashira and other cross-coupling reactions.

Basic Information

Product Name	4-Fluoro-n-(2-Methylbut-3-Yn-2-Yl)Benzamide
CAS No.	80045-51-8
Molecular Formula	C13H14FNO
Molecular Weight	219.26 g/mol
Synonyms	4-Fluoro-N-(2-methylbut-3-yn-2-yl)benzamide; N-(2-Methyl-3-butyn-2-yl)-4-fluorobenzamide; 4-Fluorobenzoic acid 1,1-dimethyl-2-propynylamide; 4-Fluoro-N-(1,1-dimethyl-2-propynyl)benzamide; Benzamide, 4-fluoro-N-(2-methyl-3-butyn-2-yl)-; 80045-51-8; 4-Fluoro-N-(2-methylbut-3-yn-2-yl)benzamide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-n-(2-Methylbut-3-Yn-2-Yl)Benzamide is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.