Description

Gastrin-Releasing Peptide CAS NO 80043-53-4 is a regulatory neuropeptide that plays a critical role in stimulating gastrin release and gastric acid secretion. This high-purity peptide is essential for advanced biomedical research and diagnostic development, offering a reliable tool for studying gastrointestinal physiology and related disorders. It is primarily utilized by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions focused on neuroendocrinology and digestive system research.

Application

• Biomedical Research: A key reagent for studying the physiological and pathophysiological roles of the gastrin-releasing peptide (GRP) receptor signaling pathway.
• Pharmaceutical Development: Used as a reference standard and active pharmaceutical ingredient (API) in the research and development of novel therapeutics targeting gastrointestinal cancers and motility disorders.
• Diagnostic Assays: Serves as a critical antigen and calibrator in the development of immunoassays (e.g., ELISA, RIA) for measuring GRP levels in clinical and research settings.
• Cell Biology Studies: Employed in in vitro cell culture models to investigate cell proliferation, differentiation, and receptor binding kinetics.
• Neuroscience Research: Utilized to explore the neuromodulatory functions of GRP in the central and peripheral nervous systems.

Basic Information

Product Name	Gastrin-Releasing Peptide
CAS No.	80043-53-4
Molecular Formula	C107H166N32O31S
Molecular Weight	~2350.7 g/mol
Synonyms	GRP; Gastrin-Releasing Peptide (1-27), human; GRP (1-27); Neuromedin C; Mammalian Bombesin; pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2; Bombesin-like peptide
EINECS	Contact for details

Quality Control

Our Gastrin-Releasing Peptide is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee traceability and compliance with research-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the product desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Assessed by receptor binding assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.