Description

Penicillin-Streptomycin is a widely used antibiotic combination solution, recognized globally under CAS No. 8025-06-7. This product is essential for preventing bacterial and fungal contamination in cell culture and bioprocessing applications, ensuring the integrity of sensitive biological research and production. It is a critical reagent for pharmaceutical manufacturers, biotechnology research laboratories, and academic institutions requiring sterile cell culture conditions.

Application

• Cell Culture Media Supplement: Primary application for preventing bacterial contamination in mammalian, insect, and plant cell cultures.
• Bioprocessing & Vaccine Production: Used in upstream processes to maintain aseptic conditions during fermentation and cell growth.
• Primary Cell Isolation & Maintenance: Added to media during tissue dissociation and subsequent culture to minimize microbial overgrowth.
• Stem Cell Research: Employed in the culture of pluripotent and mesenchymal stem cells to ensure contamination-free expansion.
• Hybridoma Technology: Used in the production and maintenance of antibody-producing hybridoma cell lines.
• In vitro Fertilization (IVF) Media: A component in certain assisted reproductive technology media preparations.
• Virology Research: Helps maintain sterile conditions during the propagation of viral stocks in cell monolayers.
• General Laboratory Sterilization: Can be used as a broad-spectrum antibiotic solution for rinsing surfaces or equipment in sterile workflows.

Basic Information

Product Name	Penicillin-Streptomycin
CAS No.	8025-06-7
Molecular Formula	Mixture
Molecular Weight	N/A (Mixture)
Synonyms	Pen-Strep; Penicillin G Sodium - Streptomycin Sulfate; Antibiotic-Antimycotic Solution (100X); Penicillin/Streptomycin Solution; Cell Culture Antibiotic; Penicillin Streptomycin Mixture; Antibiotic Solution for Cell Culture; Streptomycin-Penicillin Combination
EINECS	Contact for details

Quality Control

Our Penicillin-Streptomycin solution is manufactured under strict quality systems suitable for cell culture and research use. Each lot is tested for sterility, potency, and endotoxin levels to ensure consistent performance. Certificates of Analysis (COA) detailing assay results for Penicillin G and Streptomycin activity, pH, and clarity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -5°C to -20°C. Aliquot as needed to avoid repeated freeze-thaw cycles. Thawed working solutions can be stored at 2°C to 8°C for several weeks.

Specification

Item	Specification
Description	Clear, colorless to faint yellow solution
Identification (HPLC)	Conforms
Assay (Penicillin G)	10,000 IU/mL ± 10%
Assay (Streptomycin)	10,000 µg/mL ± 10%
pH	6.0 - 7.5
Sterility Test	Sterile
Endotoxin	< 0.25 EU/mL
Mycoplasma	Not Detected

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.