Description

Poly(n-Isopropyl Acrylamide) is a thermosensitive polymer known for its sharp lower critical solution temperature (LCST) behavior in aqueous solutions. This unique property makes it a critical material for developing smart, responsive systems in advanced research and industrial applications. It is essential for scientists and engineers in the biotechnology, pharmaceutical, and materials science sectors who require precise control over solubility and phase transitions.

Application

• Drug Delivery Systems: As a key component in stimuli-responsive hydrogels and micelles for controlled release of therapeutic agents.
• Biotechnology & Cell Culture: Used to create temperature-responsive surfaces for cell sheet engineering and non-enzymatic cell harvesting.
• Diagnostics & Biosensing: Employed in the fabrication of smart sensors and actuators where property changes are triggered by temperature.
• Advanced Material Synthesis: Serves as a building block for functional polymers, nanogels, and composite materials with tunable properties.
• Separation Technology: Utilized in chromatography and membrane science for temperature-modulated purification processes.
• Academic & Industrial R&D: A fundamental polymer for investigating phase behavior, polymer physics, and novel responsive material concepts.

Basic Information

Product Name	Poly(n-Isopropyl Acrylamide)
CAS No.	25189-55-3
Molecular Formula	(C6H11NO)n
Molecular Weight	Variable (Polymer)
Synonyms	PNIPAM; Poly(N-isopropylacrylamide); Poly(NIPAAm); N-Isopropylacrylamide polymer; Poly(N-isopropylacrylamide) homopolymer; PNIPAAm; NIPAM polymer; Thermoresponsive poly(N-isopropylacrylamide)
EINECS	Contact for details

Quality Control

Our Poly(n-Isopropyl Acrylamide) is produced under controlled conditions to ensure batch-to-batch consistency. Quality is verified through a suite of analytical techniques to confirm molecular weight distribution, purity, and functional performance. Certificates of Analysis (COA) detailing specific parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
LCST (in water)	~32°C (Typical, grade-dependent)
Molecular Weight (Mw)	Specified per grade (e.g., 10k - 500k Da)
Polydispersity Index (PDI)	< 1.5 (Typical)
Residual Monomer	< 0.5% (by HPLC)
Moisture Content	< 5.0% (by KF Titration)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.