Description

Polyornithine is a synthetic, cationic polymer of the amino acid ornithine, widely recognized for its strong positive charge and cell-adhesive properties. This compound is essential for creating a stable, positively charged surface that promotes the attachment and growth of various cell types in vitro. It is a critical material for researchers and manufacturers in the life sciences, biotechnology, and pharmaceutical development sectors, particularly for cell culture, tissue engineering, and biomedical coating applications.

Application

• Cell Culture Substrate Coating: Used to coat cultureware (e.g., plates, flasks, slides) to enhance the adhesion of primary cells, neurons, and other difficult-to-culture cell types.
• Biomedical Research: Serves as a foundational layer in studies involving cell behavior, differentiation, and tissue modeling.
• Tissue Engineering Scaffolds: Incorporated into or used to functionalize 3D scaffolds to improve cell seeding efficiency and tissue integration.
• Biochip and Biosensor Fabrication: Applied as a surface modification agent to create charged interfaces for immobilizing biomolecules like DNA or proteins.
• Neuroscience Research: Particularly valuable for promoting the growth and maintenance of neuronal cultures.
• Drug Delivery Systems: Investigated as a component in polyelectrolyte complexes or coatings for controlled release applications.

Basic Information

Product Name	Polyornithine
CAS No.	25104-12-5
Molecular Formula	(C5H12N2O2)n
Molecular Weight	Varies by chain length (n). Contact for details.
Synonyms	Poly(L-ornithine); Poly-L-ornithine; PLO; Polyornithine hydrobromide; Poly(ornithine); Poly(α,δ-diaminovaleric acid); L-Ornithine homopolymer; NSC 354731
EINECS	Contact for details.

Quality Control

Our Polyornithine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure consistency, purity, and performance for sensitive cell culture applications. Certificates of Analysis (COA) detailing key parameters such as molecular weight distribution, purity, and endotoxin levels are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C for long-term stability. Keep the container in a dry, cool, and well-ventilated area. Allow the product to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solution
Identification (IR)	Conforms to structure
Assay (Polyornithine Content)	≥ 95% (by HPLC or titration)
Molecular Weight (Average)	Customizable (e.g., 15-30 kDa, 30-70 kDa)
Endotoxin Level	< 1.0 EU/mg (for cell culture grade)
Solubility (in water)	Clear, colorless solution
pH (1% solution)	Specified range

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.