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Hydroxyapatite Type I CAS NO 130-66-5


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CAS No.:130-66-5

Grade:Pharmacy Grade

Content:99.0%

Brand:Customizable

Packaging:Customizable

Description

Hydroxyapatite Type I is a high-purity, synthetic form of calcium phosphate that closely mimics the mineral component of human bone and teeth. This biocompatibility makes it an essential material for advanced medical and dental applications where integration with biological tissue is critical. It is primarily utilized by manufacturers in the biomedical, pharmaceutical, and advanced materials sectors seeking reliable, high-quality raw materials for implants, drug delivery systems, and chromatography.

Application

  • Bone Graft Substitutes & Orthopedic Implants: Used as a bioactive scaffold or coating to promote bone regeneration and osseointegration in dental, spinal, and trauma surgeries.
  • Chromatography Media: Serves as a robust stationary phase for the purification of proteins, antibodies, and other biomolecules in downstream bioprocessing.
  • Drug Delivery Systems: Acts as a carrier for controlled release of therapeutic agents due to its porous structure and biocompatibility.
  • Dental Care & Restoratives: Incorporated into toothpaste for remineralization, and used in cements and composites for dental fillings and coatings.
  • Cosmetics & Personal Care: Utilized as a gentle abrasive in exfoliants and as an opacifying agent in various cosmetic formulations.
  • Biomedical Research: Employed as a standard or model compound in studies related to biomaterials, biomineralization, and tissue engineering.

Basic Information

Product Name Hydroxyapatite Type I
CAS No. 130-66-5
Molecular Formula Ca5(PO4)3(OH)
Molecular Weight 502.31 g/mol
Synonyms Calcium Hydroxyapatite; HAP; Hydroxylapatite; Durapatite; Calcium Phosphate Hydroxide; Tribasic Calcium Phosphate; Pentacalcium Hydroxide Tris(Orthophosphate); Osteogen; Bone Mineral
EINECS Contact for details

Quality Control

Our Hydroxyapatite Type I is manufactured under a strict quality management system. Each batch is tested to ensure it meets high-purity standards suitable for demanding applications, including biomedical and chromatographic uses. Certificates of Analysis (COA) detailing key parameters such as crystallinity, Ca/P ratio, and trace metal content are provided with every shipment to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture and CO2, which can affect performance.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to standard
Assay (as Ca5(PO4)3(OH)) ≥ 96.0 %
Calcium to Phosphorus (Ca/P) Molar Ratio 1.67 ± 0.02
Crystallinity (by XRD) ≥ 90 %
Loss on Drying ≤ 2.0 %
Heavy Metals (as Pb) ≤ 20 ppm
Specific Surface Area (BET) 40 - 100 m²/g
Particle Size Distribution (D50) Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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