Description

4-Chlorophenylacetylene is a versatile halogenated alkyne building block, essential for advanced organic synthesis. Its terminal alkyne functionality and aromatic chlorination make it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications such as cross-coupling reactions and polymer synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via Sonogashira, Heck, and other cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogen and alkyne groups for structural diversification.
• Material Science & Polymer Chemistry: Serves as a monomer or functionalizing agent for creating specialty polymers, conductive materials, and liquid crystals.
• Organic Ligand & Catalyst Development: Employed in the synthesis of novel ligands for transition metal catalysts used in homogeneous catalysis.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new synthetic methodologies and creating molecular libraries.
• Fine Chemical Production: Intermediate in the manufacture of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	4-Chlorophenylacetylene
CAS No.	873-73-4
Molecular Formula	C8H5Cl
Molecular Weight	136.58 g/mol
Synonyms	1-Chloro-4-ethynylbenzene; p-Chlorophenylacetylene; 4-Ethynylchlorobenzene; (4-Chlorophenyl)acetylene; 1-Ethynyl-4-chlorobenzene; p-Ethynylchlorobenzene; 4-Chloroethynylbenzene
EINECS	212-842-5

Quality Control

Our 4-Chlorophenylacetylene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.