Description

Lithium Methoxide is a powerful alkali metal alkoxide compound, widely recognized for its role as a versatile base and catalyst in organic synthesis. Its high reactivity and strong basicity make it a critical reagent for driving complex chemical transformations efficiently and with high selectivity. This product is essential for manufacturers and R&D facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to optimize condensation, esterification, and transesterification reactions.

Application

• Pharmaceutical Synthesis: A key reagent in the production of active pharmaceutical ingredients (APIs), particularly for condensation reactions and as a catalyst in the synthesis of complex organic molecules.
• Biodiesel Production: Employed as a highly effective transesterification catalyst for converting triglycerides into fatty acid methyl esters (FAME).
• Polymer & Resin Manufacturing: Used as an initiator or catalyst in polymerization processes and the production of specialty polymers and resins.
• Fine Chemical Synthesis: Acts as a strong base in various organic synthesis steps, including deprotonation, alkoxide formation, and the synthesis of esters and ethers.
• Agrochemical Formulation: Utilized in the synthesis of certain pesticides and herbicides where its strong basic properties are required for specific intermediate reactions.
• Cross-Coupling Reactions: Serves as a base in palladium-catalyzed cross-coupling reactions, such as Suzuki and Heck reactions, which are pivotal in creating complex carbon-carbon bonds.

Basic Information

Product Name	Lithium Methoxide
CAS No.	865-34-9
Molecular Formula	CH3OLi
Molecular Weight	37.98 g/mol
Synonyms	Lithium Methoxide; Methanol, lithium salt; Lithium Methylate; Lithium Methanolate; Methyl alcohol, lithium salt; Lithium methoxide solution; Methoxylithium; LiOMe
EINECS	212-737-7

Quality Control

Our Lithium Methoxide is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing key parameters such as assay, moisture content, and impurity profiles. Our quality system is designed to meet the rigorous demands of pharmaceutical and fine chemical applications, ensuring reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability of solutions; solid forms are typically stored at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white powder or solution
Identification (IR)	Conforms
Assay (Lithium Methoxide)	≥ 95.0 %
Assay (by Titration)	Contact for details
Moisture (Karl Fischer)	≤ 1.0 %
Lithium Hydroxide (LiOH)	≤ 2.0 %
Lithium Carbonate (Li2CO3)	≤ 1.0 %
Solvent Content (for solutions)	Specified per grade

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.