Description

Cyclo(L-Asn-L-Gln-L-Tyr-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Trp-D-Phe-) is a synthetic cyclic decapeptide with a complex, well-defined structure. This compound is of significant interest for advanced research and development in the pharmaceutical and biotechnology sectors due to its potential as a bioactive scaffold or a reference standard. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptide-based drug discovery, structure-activity relationship (SAR) studies, and biochemical analysis.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery and development of novel peptide-based therapeutics.
• Biochemical Research: Used as a tool compound for studying peptide-protein interactions, enzyme inhibition, and receptor binding assays.
• Structure-Activity Relationship (SAR) Studies: Provides a defined cyclic peptide backbone for modifying side chains to investigate biological activity and optimize pharmacological properties.
• Academic Research: Employed in university and institutional labs for fundamental studies in peptide chemistry, conformational analysis, and medicinal chemistry.
• High-Purity Reference Standard: Used for analytical method development, validation, and quality control in laboratories requiring certified reference materials.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the synthesis of more complex peptide conjugates or molecular probes.

Basic Information

Product Name	Cyclo(L-Asn-L-Gln-L-Tyr-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Trp-D-Phe-)
CAS No.	865-28-1
Molecular Formula	C68H88N14O15
Molecular Weight	1293.5 g/mol
Synonyms	Cyclo(Asn-Gln-Tyr-Val-Orn-Leu-D-Phe-Pro-Trp-D-Phe); Cyclic Decapeptide (Asn, Gln, Tyr, Val, Orn, Leu, D-Phe, Pro, Trp, D-Phe); Cyclo(L-Asparaginyl-L-glutaminyl-L-tyrosyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-tryptophyl-D-phenylalanine); 865-28-1; Cyclo(NGQYVOLfPWf); [Cyclo(1-10)]NGQYVOLfPWf
EINECS	Contact for details

Quality Control

Our Cyclo(L-Asn-L-Gln-L-Tyr-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Trp-D-Phe-) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets exacting specifications for research use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.