Description

Cefaloram CAS NO 859-07-4 is a semi-synthetic cephalosporin antibiotic belonging to the first-generation class. This compound is valued for its broad-spectrum antibacterial activity against both Gram-positive and Gram-negative organisms. It is primarily utilized in pharmaceutical research and development for the synthesis of active pharmaceutical ingredients (APIs) and as a critical reference standard in analytical laboratories.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced cephalosporin antibiotic formulations.
• Reference Standard: Used in quality control laboratories for HPLC, LC-MS, and other analytical methods to identify and quantify related substances.
• Antibacterial Research: Serves as a model compound in microbiological studies to evaluate mechanisms of action and resistance.
• API Manufacturing: Employed in the production of finished dosage forms under current Good Manufacturing Practice (cGMP) environments.
• Veterinary Medicine: Investigated for use in developing antibacterial treatments for animal health.

Basic Information

Product Name	Cefaloram
CAS No.	859-07-4
Molecular Formula	C20H20N6O6S2
Molecular Weight	512.54 g/mol
Synonyms	Cephaloram; 7-[(2-Amino-2-phenylacetamido)]-3-[(5-methyl-1,3,4-thiadiazol-2-yl)thiomethyl]-3-cephem-4-carboxylic Acid; (6R,7R)-7-[(R)-2-Amino-2-phenylacetamido]-3-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Antibiotic 87/312; Cefaloramum; SQ 14,512
EINECS	Contact for details

Quality Control

Our Cefaloram is manufactured and tested to meet high-purity standards suitable for research and pharmaceutical applications. Each batch undergoes rigorous analysis including identification, assay, and impurity profiling via advanced chromatographic techniques. A comprehensive Certificate of Analysis (COA) is provided, detailing results for purity, related substances, residual solvents, and other critical parameters to ensure compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.