Description

Tris(4-Methoxyphenyl)Phosphine is a specialized organophosphorus compound characterized by its three methoxy-substituted phenyl groups attached to a central phosphorus atom. This structure makes it a valuable ligand and reagent in transition metal-catalyzed cross-coupling reactions, where it facilitates key bond-forming steps with high efficiency. It is primarily sought after by pharmaceutical intermediates, agrochemical, and advanced materials research and development sectors for synthesizing complex organic molecules.

Application

• Ligand in Palladium-Catalyzed Cross-Coupling Reactions: Essential for Suzuki, Heck, and Stille couplings in pharmaceutical and fine chemical synthesis.
• Pharmaceutical Intermediate Manufacturing: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Employed in creating advanced pesticides and herbicides requiring precise molecular architecture.
• Material Science Research: Acts as a precursor or stabilizing agent in the development of organic electronic materials and catalysts.
• Organic Synthesis Reagent: Facilitates nucleophilic substitution and other phosphorus-mediated transformations in laboratory and pilot-scale processes.
• Catalyst Development: Used to synthesize and modify homogeneous catalysts for specialized industrial processes.

Basic Information

Product Name	Tris(4-Methoxyphenyl)Phosphine
CAS No.	855-38-9
Molecular Formula	C21H21O3P
Molecular Weight	352.36 g/mol
Synonyms	Tris(p-anisyl)phosphine; Tri(4-methoxyphenyl)phosphine; Phosphorous tris(4-methoxyphenyl); P(4-MeOC6H4)3; Tris(4-methoxyphenyl)phosphane; 4-Methoxyphenylphosphine, tris-; Tris(p-methoxyphenyl)phosphine
EINECS	212-700-5

Quality Control

Our Tris(4-Methoxyphenyl)Phosphine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity, the product should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.