Description

Naphazoline is a potent imidazoline derivative with significant vasoconstrictive properties. This compound is a critical active pharmaceutical ingredient (API) valued for its efficacy in reducing redness and swelling. It is primarily required by pharmaceutical manufacturers and research institutions for ophthalmic and nasal decongestant formulations. Our supply ensures high purity and consistent quality for reliable production and development.

Application

• Primary Active Pharmaceutical Ingredient (API) in over-the-counter (OTC) eye drops for the relief of ocular redness and irritation.
• Key component in nasal spray formulations designed to alleviate symptoms of nasal congestion and rhinitis.
• Intermediate in the synthesis of more complex pharmaceutical compounds within the imidazoline class.
• Reference standard in analytical laboratories for quality control and method development using HPLC or GC.
• Research chemical in pharmacological studies investigating adrenergic receptor activity and vascular physiology.

Basic Information

Product Name	Naphazoline
CAS No.	835-31-4
Molecular Formula	C14H14N2
Molecular Weight	210.28 g/mol
Synonyms	2-(1-Naphthylmethyl)-2-imidazoline; Naphazoline Hydrochloride (Salt form); Privine; Albalon; Naphcon; Vasocon; 4,5-Dihydro-2-(1-naphthalenylmethyl)-1H-imidazole; Benzimidazole, 2-(naphth-1-ylmethyl)-4,5-dihydro-
EINECS	212-658-0

Quality Control

Our Naphazoline is produced and tested under strict quality management systems. We provide material that meets or exceeds relevant pharmacopeial standards, including USP and EP monographs where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to ensure full traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.