Description

Glpg1837 is a high-purity, non-peptidic small molecule compound identified by the CAS number 1654725-02-6. This compound is of significant interest in pharmaceutical research and development, particularly as a potential therapeutic agent or a key synthetic intermediate. It is primarily utilized by R&D scientists and process chemists in the life sciences sector. Its well-defined chemical structure makes it a critical component for advancing drug discovery programs and developing robust manufacturing processes.

Application

• Pharmaceutical Research: Serves as a lead compound or reference standard in drug discovery for specific biological targets.
• Preclinical Development: Used in pharmacological and toxicological studies to evaluate efficacy and safety profiles.
• Chemical Synthesis: Acts as a crucial building block or intermediate in the multi-step synthesis of more complex active pharmaceutical ingredients (APIs).
• Biochemical Assays: Employed as a tool compound to study enzyme inhibition, receptor binding, or other molecular interactions in vitro.
• Process Chemistry: Used for route scouting, optimization, and scale-up studies under Good Manufacturing Practice (GMP) guidelines.
• Analytical Method Development: Functions as a high-purity standard for developing and validating HPLC, LC-MS, or other analytical techniques.

Basic Information

Product Name	Glpg1837
CAS No.	1654725-02-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GLPG-1837; GLPG 1837; 1654725-02-6; UNII-8F1S6U3G4F; 8F1S6U3G4F; (S)-N-(3-(2-(2,6-Dichloro-3,5-dimethoxyphenyl)pyrimidin-4-yl)phenyl)-2-((4-ethylpiperazin-1-yl)methyl)-1-oxo-2,7-diazaspiro[4.4]nonane-7-carboxamide
EINECS	Contact for details

Quality Control

Our Glpg1837 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced chromatographic and spectroscopic methods. We adhere to relevant industry standards, and custom synthesis or specific analytical protocols can be discussed to meet your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.