Description

Aviptadil Acetate is a synthetic vasoactive intestinal peptide (VIP) analogue, a peptide of significant pharmacological interest. Its primary value lies in its potent bronchodilatory and anti-inflammatory properties, making it a critical compound for advanced research and development. This product is essential for pharmaceutical R&D teams, academic researchers, and manufacturers focused on developing novel therapeutics for respiratory conditions, inflammatory diseases, and neurological disorders.

Application

• Pharmaceutical Research & Development: As a key active pharmaceutical ingredient (API) or intermediate in the development of new drugs targeting pulmonary arterial hypertension (PAH), acute respiratory distress syndrome (ARDS), and asthma.
• Preclinical & Clinical Studies: Utilized in laboratory and clinical investigations to study VIP receptor (VPAC1/VPAC2) signaling pathways and therapeutic efficacy.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Used in studies exploring neuroprotection, immunomodulation, and smooth muscle relaxation mechanisms.
• Peptide Chemistry: Acts as a model compound for studying peptide stability, formulation, and delivery systems.

Basic Information

Product Name	Aviptadil Acetate
CAS No.	1444827-29-5
Molecular Formula	C₁₄₇H₂₃₈N₄₄O₄₅S • xC₂H₄O₂
Molecular Weight	3325.8 g/mol (free base)
Synonyms	Vasoactive Intestinal Peptide (human, porcine, rat); VIP, human; PHI-27; Peptide Histidine Isoleucine; PHM-27; Aviptadil; RLF-100; Vasoactive Intestinal Contractor; PHI; PHM
EINECS	Contact for details

Quality Control

Our Aviptadil Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents, ensuring it meets stringent standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Unknown Impurity	≤ 2.0%
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	3.0 - 10.0%
Peptide Content (Amino Acid Analysis)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.