Description

Almitrine is a synthetic chemical compound with significant pharmacological activity, primarily known for its role as a respiratory stimulant. Its value lies in its ability to act as a selective chemoreceptor agonist, making it a critical intermediate in the research and development of therapeutic agents. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) targeting respiratory and neurological conditions.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of respiratory stimulant drugs.
• Biomedical Research: Used in preclinical studies to investigate mechanisms of peripheral chemoreceptor activation and hypoxic pulmonary vasoconstriction.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• API Development: Integral in the development and scale-up processes for new chemical entities (NCEs) targeting chronic obstructive pulmonary disease (COPD) and sleep apnea.
• Academic Studies: Utilized in university and institutional research exploring cardiopulmonary physiology and pharmacology.

Basic Information

Product Name	Almitrine
CAS No.	27469-53-0
Molecular Formula	C26H29F2N7
Molecular Weight	477.55 g/mol
Synonyms	Almitrine; Almitrine dimesylate (salt form); S-2620; Vectarion; 2,4-Bis(allylamino)-6-[4-(bis(4-fluorophenyl)methyl)-1-piperazinyl]-1,3,5-triazine; 6-[4-[Bis(4-fluorophenyl)methyl]-1-piperazinyl]-2,4-bis(2-propen-1-ylamino)-1,3,5-triazine
EINECS	Contact for details

Quality Control

Our Almitrine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.