Description

2-(4-Fluorophenyl)Succinic Acid is a high-purity fluorinated organic building block of significant commercial and research interest. This compound serves as a critical chiral intermediate in the synthesis of advanced pharmaceutical active ingredients and fine chemicals. Industries such as pharmaceutical development, agrochemical research, and specialty chemical manufacturing rely on its consistent quality and reliable supply for their complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorophenyl moiety for enhanced biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic molecules used in electronic displays and optoelectronic devices.
• Peptide Mimetics & Bio-conjugates: The succinic acid backbone allows for incorporation into peptide chains and bioconjugation linkers for drug delivery systems.
• Asymmetric Catalyst Ligand Synthesis: Utilized in the preparation of chiral ligands for asymmetric hydrogenation and other catalytic processes.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with unique thermal and chemical properties.

Basic Information

Product Name	2-(4-Fluorophenyl)Succinic Acid
CAS No.	833-18-1
Molecular Formula	C10H9FO4
Molecular Weight	212.17 g/mol
Synonyms	4-Fluorophenylsuccinic Acid; (4-Fluorophenyl)butanedioic Acid; 2-(p-Fluorophenyl)succinic Acid; DL-2-(4-Fluorophenyl)succinic Acid; (±)-2-(4-Fluorophenyl)succinic Acid; Butanedioic acid, 2-(4-fluorophenyl)-; NSC 163049; 4-Fluorobenzylsuccinic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Fluorophenyl)Succinic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards, and our quality commitment includes traceability and batch-to-batch consistency. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.