Description

n-Acetyl-2-Bromo-5-Chloroaniline is a high-purity halogenated aniline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized aromatic scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific bromo and chloro substituents in a controlled manner.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the halogenated aniline core contributes to biological activity.
• Dye and Pigment Manufacturing: Serves as a precursor for synthesizing specialized azo dyes and high-performance pigments.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional materials.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to create biaryl structures.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	n-Acetyl-2-Bromo-5-Chloroaniline
CAS No.	827-66-7
Molecular Formula	C8H7BrClNO
Molecular Weight	248.50 g/mol
Synonyms	2-Bromo-5-Chloroacetanilide; N-(2-Bromo-5-chlorophenyl)acetamide; Acetamide, N-(2-bromo-5-chlorophenyl)-; 1-Acetamido-2-bromo-5-chlorobenzene; 2'-Bromo-5'-chloroacetanilide; N-Acetyl-2-bromo-5-chloroaniline; 827-66-7; 2-Bromo-5-chloro-N-acetylaniline
EINECS	Contact for details

Quality Control

Our n-Acetyl-2-Bromo-5-Chloroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements of our global clientele in research and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.