Description

4-Fluorobenzamide is a versatile fluorinated aromatic amide building block with significant utility in advanced organic synthesis. Its value lies in the unique reactivity of the fluorine substituent and the amide functional group, enabling precise molecular construction for high-value intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors, where it serves as a key precursor for active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and pesticides, where the fluorine atom improves biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering their surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: Functions as a versatile reagent in cross-coupling reactions, amide bond transformations, and as a directing group in metal-catalyzed C-H functionalization.
• Biochemical Research: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a probe molecule in biochemical assays.

Basic Information

Item	Details
Product Name	4-Fluorobenzamide
CAS No.	824-75-9
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	p-Fluorobenzamide; 4-Fluorobenzoic acid amide; Benzoamide, 4-fluoro-; FBA; 4-Fluorobenzene-1-carboxamide; 4-Fluorobenzoylamide; 4-Fluorobenzene carboxamide; p-Fluorobenzoylamide
EINECS	212-534-8

Quality Control

Our 4-Fluorobenzamide is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	168°C - 172°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.