Description

n-Methyl-2,2,2-trifluoroacetamide is a specialized fluorinated acetamide derivative with the CAS number 815-06-5. This compound serves as a versatile and valuable fluorine-containing building block in advanced organic synthesis, enabling the introduction of the trifluoromethyl group into target molecules. It is primarily utilized by pharmaceutical, agrochemical, and material science research and development teams for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoroacetamide or trifluoromethyl moiety to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine atoms contribute to improved efficacy and environmental profile.
• Organic Synthesis Reagent: Acts as a versatile reagent for N-methylation and acylation reactions, especially in the synthesis of complex heterocycles and fluorinated analogs.
• Material Science Precursor: Employed in the research and development of fluorinated polymers, liquid crystals, and other specialty materials with unique surface and electronic properties.
• Chemical Research: Serves as a standard or starting material in academic and industrial R&D labs exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	n-Methyl-2,2,2-trifluoroacetamide
CAS No.	815-06-5
Molecular Formula	C3H4F3NO
Molecular Weight	127.06 g/mol
Synonyms	N-Methyltrifluoroacetamide; 2,2,2-Trifluoro-N-methylacetamide; Methyltrifluoroacetamide; Trifluoro-N-methylacetamide; N-Methyl-2,2,2-trifluoroacetamide; Acetamide, N-methyl-2,2,2-trifluoro-; TFA-NMe; MTA
EINECS	Contact for details

Quality Control

Our n-Methyl-2,2,2-trifluoroacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.