Description

Coenzyme A is a fundamental cofactor essential for numerous enzymatic reactions in cellular metabolism, particularly in the transfer of acyl groups. Its reliable supply and consistent high purity are critical for research and production processes where metabolic pathway integrity is non-negotiable. This vital biochemical is indispensable for manufacturers and researchers in the pharmaceutical, biotechnology, and nutraceutical industries, as well as in academic research focused on biochemistry and metabolic engineering.

Application

• Biopharmaceutical Manufacturing: Used as a critical component in cell culture media and fermentation processes for the production of complex therapeutic compounds.
• Enzymatic Synthesis: Serves as a co-substrate in the enzymatic production of fine chemicals, antibiotics, and specialty esters.
• Diagnostic Reagent Formulation: A key ingredient in diagnostic kits and assays that measure enzyme activities like citrate synthase or for metabolic profiling.
• Biochemical Research: Essential for in vitro studies of metabolic pathways, including the citric acid cycle, fatty acid synthesis, and oxidation.
• Nutraceutical & Cosmetic Ingredient: Investigated for use in advanced supplements and skincare products targeting cellular energy and regeneration.
• Food Science Research: Applied in studies related to flavor compound development and food preservation mechanisms.

Basic Information

Product Name	Coenzyme A
CAS No.	85-61-0
Molecular Formula	C21H36N7O16P3S
Molecular Weight	767.53 g/mol
Synonyms	CoA; CoASH; Coenzyme A (free acid); CoA-SH; Acetylcoenzyme A synthase cofactor; Vitamin B5 derivative; Pantothenic acid derivative; 3'-Phosphoadenosine 5'-diphospho-pantetheine
EINECS	201-619-0

Quality Control

Our Coenzyme A is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material that meets the exacting standards required for research, diagnostic, and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For extended storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	2.5 - 4.0
Specific Rotation	-2.5° to -3.5°
UV Absorbance Ratio (A260/A280)	0.80 - 0.90
Biological Activity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.