Description

Lignoceroyl Coenzyme A (Ammonium Salt) is a high-purity, long-chain fatty acyl-CoA derivative, a critical biochemical reagent for in vitro enzymatic studies. This compound serves as a specific substrate for enzymes involved in lipid metabolism, fatty acid elongation, and sphingolipid biosynthesis pathways. It is essential for researchers and process developers in pharmaceutical R&D, biotechnology, and academic biochemistry who require reliable, well-characterized cofactors to study and modulate complex metabolic processes.

Application

• Enzymology Research: As a defined substrate for acyl-CoA synthetases, acyltransferases, and elongases (ELOVL family) to study kinetics and inhibition.
• Lipidomics & Metabolic Pathway Analysis: Used in tracer studies and in vitro reconstitution assays to investigate very long-chain fatty acid (VLCFA) synthesis.
• Drug Discovery Screening: Employed in high-throughput assays to identify potential therapeutics targeting metabolic disorders like X-linked adrenoleukodystrophy (X-ALD).
• Biochemical Standard: Serves as a quantitative standard in LC-MS/MS for the analysis of cellular acyl-CoA pools.
• Sphingolipid Biosynthesis Studies: Acts as a precursor in the study of ceramide and sphingomyelin synthesis pathways.
• Industrial Enzyme Characterization: Used to test the activity and specificity of engineered enzymes for biocatalytic synthesis of specialty lipids.

Basic Information

Product Name	Lignoceroyl Coenzyme A (Ammonium Salt)
CAS No.	799812-99-0
Molecular Formula	C45H84N7O17P3S
Molecular Weight	1128.13 g/mol
Synonyms	Lignoceroyl-CoA ammonium salt; Tetracosanoyl-CoA; C24:0-CoA; Coenzyme A, S-tetracosanoate; Tetracosanoic acid, coenzyme A derivative; Arachidic acid-CoA (common misnomer); Very Long-Chain Acyl-CoA; VLCFA-CoA Substrate
EINECS	Contact for details

Quality Control

Our Lignoceroyl Coenzyme A (Ammonium Salt) is manufactured under controlled conditions to ensure batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot into single-use vials to minimize freeze-thaw cycles and maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic/UV)	≥ 90% (as ammonium salt)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO (limited)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.