Description

Tricosanoyl Coenzyme A (Ammonium Salt) is a specialized, high-purity biochemical reagent essential for research and development in lipid metabolism and enzyme function studies. This compound serves as a critical substrate or inhibitor for investigating the activity of acyl-CoA synthetases and other enzymes involved in very-long-chain fatty acid processing. It is primarily utilized by pharmaceutical researchers, academic biochemists, and diagnostic kit manufacturers focused on metabolic disorders and lipidomics. The product is supplied as an ammonium salt to enhance its stability and solubility for experimental use.

Application

• Enzymology Research: Used as a substrate for studying the kinetics and specificity of acyl-CoA synthetases, particularly those acting on very-long-chain fatty acids.
• Lipid Metabolism Studies: Essential for in vitro assays modeling fatty acid activation, β-oxidation pathways, and complex lipid biosynthesis.
• Drug Discovery & Screening: Serves as a key reagent in high-throughput screening platforms targeting metabolic enzymes for therapeutic intervention.
• Diagnostic Development: Employed in the formulation of calibrators and controls for clinical assays measuring specific enzyme deficiencies.
• Biochemical Tool Compound: Acts as a precise molecular tool to probe protein-ligand interactions and metabolic flux in cell-based systems.
• Academic & Industrial R&D: Supports fundamental and applied research in biochemistry, molecular biology, and nutrition science.

Basic Information

Product Name	Tricosanoyl Coenzyme A (Ammonium Salt)
CAS No.	799812-97-8
Molecular Formula	C44H79N7O17P3S • xNH3
Molecular Weight	~1122.0 g/mol (Free acid)
Synonyms	Tricosanoyl-CoA ammonium salt; Coenzyme A, S-tricosanoate, ammonium salt; C23:0-CoA; Tricosanoyl-Coenzyme A ammonium salt; Very Long-Chain Acyl-CoA (C23:0); Arachidoyl-CoA (common name for C20:0, verify chain length); Acyl-Coenzyme A (C23:0); 23:0 CoA
EINECS	Contact for details

Quality Control

Our Tricosanoyl Coenzyme A (Ammonium Salt) is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including purity assessment by HPLC and structural confirmation by mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and specific tests is provided with every shipment. We adhere to ISO 9001 quality management principles, and production can be aligned with GMP standards for critical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is hygroscopic and must be handled in a dry environment. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Enzymatic/UV)	≥ 90% (CoA content)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.