Description

(1R,2R)-2-Amino-1-Phenylpropyldiphenylphosphine, Min. 97% is a high-purity chiral phosphine ligand, a critical building block in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in catalytic reactions, directly impacting the efficiency and cost of producing optically active compounds. This product is essential for research and process development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral auxiliaries for complex synthesis.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric hydrogenation and cross-coupling reactions.
• Critical component in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Use in the development of agrochemicals and other bioactive molecules where chirality influences activity.
• Employed in academic and industrial research for developing new catalytic methodologies.
• As a precursor or intermediate for the synthesis of more complex, tailored phosphine ligands.
• Facilitates the production of flavors, fragrances, and other specialty fine chemicals.

Basic Information

Product Name	(1R,2R)-2-Amino-1-Phenylpropyldiphenylphosphine
CAS No.	799297-44-2
Molecular Formula	C21H22NP
Molecular Weight	319.38 g/mol
Synonyms	(1R,2R)-(-)-2-Amino-1-phenyl-1-propyldiphenylphosphine; (1R,2R)-2-Amino-1-phenylpropyl(diphenyl)phosphine; (R,R)-2-Amino-1-phenylpropyldiphenylphosphine; (1R,2R)-APDPP; (R,R)-APDPP; (1R,2R)-Amino Phenyl Propyldiphenylphosphine; (R,R)-1-Phenyl-2-aminopropyldiphenylphosphine
EINECS	Contact for details

Quality Control

Our (1R,2R)-2-Amino-1-Phenylpropyldiphenylphosphine is manufactured under strict quality protocols to ensure batch-to-batch consistency and a minimum purity of 97%. Each lot is analyzed using advanced techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity, the container should be kept tightly sealed when not in use to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0%
Loss on Drying	Max. 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.