Description

Benzene, 4-(Difluoromethoxy)-2-Methyl-1-Nitro- (9Ci) CAS NO 795303-16-1 is a specialized aromatic nitro compound featuring a difluoromethoxy substituent, making it a valuable fluorinated intermediate for advanced synthesis. This compound is engineered to provide a precise chemical building block for the development of novel active ingredients, where the fluorine atoms and nitro group are critical for modulating biological activity and physicochemical properties. It is primarily targeted at research and development chemists in the pharmaceutical and agrochemical industries who require high-purity, structurally complex intermediates for their discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a fluorinated building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the research and development of specialty polymers and advanced materials where fluorinated aromatic units impart unique stability and surface properties.
• Organic Synthesis: Employed as a versatile intermediate in academic and industrial laboratories for constructing complex molecules, leveraging the reactivity of the nitro group and the stability of the difluoromethoxy moiety.
• Liquid Crystal & Electronic Chemicals: Potential use in the synthesis of fluorinated components for liquid crystal displays (LCDs) and organic electronic materials.

Basic Information

Product Name	Benzene, 4-(Difluoromethoxy)-2-Methyl-1-Nitro- (9Ci)
CAS No.	795303-16-1
Molecular Formula	C8H7F2NO3
Molecular Weight	203.14 g/mol
Synonyms	4-(Difluoromethoxy)-2-methyl-1-nitrobenzene; 2-Methyl-4-(difluoromethoxy)nitrobenzene; 1-Nitro-4-(difluoromethoxy)-2-methylbenzene; 2-Methyl-1-nitro-4-(difluoromethoxy)benzene; Nitrobenzene, 4-(difluoromethoxy)-2-methyl-; Benzene, 1-(difluoromethoxy)-2-methyl-4-nitro-; 795303-16-1 (CAS Index Name)
EINECS	Contact for details

Quality Control

Our Benzene, 4-(Difluoromethoxy)-2-Methyl-1-Nitro- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR and IR for structural confirmation, and GC for residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Single Maximum Impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.