Description

(1S,1μs,2R,2μr)-2,2μ-Di-tert-Butyl-2,3,2μ,3μ-Tetrahydro-1H,1μh(1,1μ)Biisophosphindolyl is a sophisticated chiral organophosphorus compound, valued for its unique sterically hindered and electron-rich phosphine framework. This compound is a critical ligand precursor or catalyst component in advanced asymmetric synthesis, enabling high selectivity and yield in challenging transformations. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and specialty materials.

Application

• Asymmetric Catalysis: As a chiral ligand or ligand precursor in transition metal-catalyzed reactions such as hydrogenation, cross-coupling, and hydroformylation.
• Pharmaceutical Intermediate Synthesis: For the stereoselective construction of complex molecules in API (Active Pharmaceutical Ingredient) development.
• Agrochemical Research: In the synthesis of chiral pesticides, herbicides, and plant growth regulators requiring specific stereochemistry.
• Material Science: As a building block for chiral polymers or as a modifier for surfaces in sensor technology.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and organometallic chemistry.
• Fine Chemical Production: For the manufacture of high-value, optically pure specialty chemicals and flavors/fragrances.

Basic Information

Product Name	(1S,1μs,2R,2μr)-2,2μ-Di-tert-Butyl-2,3,2μ,3μ-Tetrahydro-1H,1μh(1,1μ)Biisophosphindolyl
CAS No.	795290-34-5
Molecular Formula	C26H44P2
Molecular Weight	418.57 g/mol
Synonyms	(1S,1's,2R,2'r)-2,2'-Di-tert-butyl-2,3,2',3'-tetrahydro-1H,1'H-[1,1']biisophosphindolyl; (S,R)-DuanPhos (common ligand name); 2,2'-Di-tert-butyl-2,3,2',3'-tetrahydro-1H,1'H-[1,1']biisophosphindole; Chiral biisophosphindole ligand; Sterically hindered phosphine; CAS 795290-34-5.
EINECS	Contact for details

Quality Control

Every batch of our (1S,1μs,2R,2μr)-2,2μ-Di-tert-Butyl-2,3,2μ,3μ-Tetrahydro-1H,1μh(1,1μ)Biisophosphindolyl undergoes rigorous analytical testing to ensure high chemical and chiral purity, critical for reproducible performance in sensitive catalytic applications. Our quality protocols are designed to meet the stringent requirements of R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.