Description

4-Pentenenitrile,5-[(4S)-2,2-Dimethyl-1,3-Dioxolan-4-Yl]-3-Hydroxy-2-Methylene-,(4E)-(9Ci) is a high-value, optically active nitrile derivative featuring a protected diol moiety and a conjugated alkene-nitrile system. This compound serves as a critical chiral building block and advanced synthetic intermediate in the production of complex pharmaceuticals and fine chemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, or neurological drugs.
• Asymmetric Synthesis: Utilized as a versatile chiral synthon in stereoselective carbon-carbon bond formation and cyclization reactions.
• Natural Product Synthesis: Building block for the total synthesis of complex natural products containing nitrile and diol functionalities.
• Agrochemical Research: Intermediate in developing novel, optically active pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts.
• Material Science Research: Potential monomer or precursor for specialized polymers with unique optical or electronic properties.

Basic Information

Item	Details
Product Name	4-Pentenenitrile,5-[(4S)-2,2-Dimethyl-1,3-Dioxolan-4-Yl]-3-Hydroxy-2-Methylene-,(4E)-(9Ci)
CAS No.	794527-75-6
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	(4E)-5-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-3-hydroxy-2-methylenepent-4-enenitrile; (4E)-5-[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]-3-hydroxy-2-methylenepent-4-ennitrile; 4-Pentenenitrile, 5-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-hydroxy-2-methylene-, (4E)-; Chiral Dioxolane Nitrile Intermediate; (S)-Isomer of the Protected Hydroxy Nitrile
EINECS	Contact for details

Quality Control

Our 4-Pentenenitrile,5-[(4S)-2,2-Dimethyl-1,3-Dioxolan-4-Yl]-3-Hydroxy-2-Methylene-,(4E)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.