Description

2-(Dicyclohexylphosphino)-1-(2,4,6-Trimethyl-Phenyl)-1H-Imidazole CAS NO 794527-14-3 is a specialized, high-performance phosphine ligand widely used in transition metal catalysis. Its core value lies in its exceptional ability to facilitate challenging cross-coupling and hydrogenation reactions, offering superior selectivity and yield for the synthesis of complex molecules. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity catalysts for fine chemical manufacturing.

Application

• Pharmaceutical Intermediate Synthesis: A key ligand for Buchwald-Hartwig amination, Suzuki-Miyaura, and other C-C/C-N cross-coupling reactions critical for constructing active pharmaceutical ingredients (APIs).
• Agrochemical Production: Enables efficient catalytic steps in the manufacture of complex herbicides, fungicides, and insecticides.
• Advanced Material Development: Used in catalytic processes for creating organic electronic materials, polymers, and liquid crystals.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new catalytic transformations in laboratory settings.
• Homogeneous Catalysis: Forms active complexes with palladium, nickel, and other transition metals for highly selective hydrogenation and reduction reactions.
• Process Chemistry Optimization: Employed to improve the efficiency, scalability, and sustainability of existing industrial chemical processes.

Basic Information

Product Name	2-(Dicyclohexylphosphino)-1-(2,4,6-Trimethyl-Phenyl)-1H-Imidazole
CAS No.	794527-14-3
Molecular Formula	C24H35N2P
Molecular Weight	382.52 g/mol
Synonyms	2-(Dicyclohexylphosphino)-1-(2,4,6-trimethylphenyl)-1H-imidazole; DcypTMI; 1-(2,4,6-Trimethylphenyl)-2-(dicyclohexylphosphino)imidazole; Imidazole, 2-(dicyclohexylphosphino)-1-(2,4,6-trimethylphenyl)-; Phosphine ligand DcypTMI; 794527-14-3; 2-(Dicyclohexylphosphanyl)-1-(2,4,6-trimethylphenyl)imidazole
EINECS	Contact for details

Quality Control

Our 2-(Dicycyclohexylphosphino)-1-(2,4,6-Trimethyl-Phenyl)-1H-Imidazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and elemental analysis. Certificates of Analysis (COA) detailing purity and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.