Description

2-Chloro-N-[1-(2,4-difluorophenyl)ethyl]acetamide is a specialized fluorinated acetamide derivative, a key building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which incorporates both halogen and fluorine substituents to modulate reactivity and biological activity. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates. The compound, identified by CAS number 793727-51-2, is supplied to meet the stringent purity requirements of modern process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the difluorophenyl moiety can enhance bioavailability and environmental stability.
• Chemical Biology Probe: Acts as a versatile scaffold for creating molecular probes to study enzyme function and protein-ligand interactions in biochemical assays.
• Material Science Precursor: Employed in the synthesis of specialty polymers and liquid crystals, where its structure can impart specific electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-N-[1-(2,4-difluorophenyl)ethyl]acetamide
CAS No.	793727-51-2
Molecular Formula	C10H10ClF2NO
Molecular Weight	233.64 g/mol
Synonyms	2-Chloro-N-(1-(2,4-difluorophenyl)ethyl)acetamide; N-(1-(2,4-Difluorophenyl)ethyl)-2-chloroacetamide; 2-Chloroacetamide, N-[1-(2,4-difluorophenyl)ethyl]-; α-Chloro-N-[1-(2,4-difluorophenyl)ethyl]acetamide; Acetamide, 2-chloro-N-[1-(2,4-difluorophenyl)ethyl]-; 793727-51-2; 2-Chloro-N-(α-methyl-2,4-difluorobenzyl)acetamide
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-N-[1-(2,4-difluorophenyl)ethyl]acetamide is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.