Description

4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylicacid,6-(1-Hydroxyethyl)-3-Methyl-7-Oxo-,(5Alpha,6Bta)-(9Ci) is a high-purity advanced pharmaceutical intermediate with the CAS registry number 793618-48-1. This compound is a critical building block in the synthesis of modern β-lactam antibiotics, offering a precise stereochemical configuration essential for biological activity. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of novel antibacterial agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of next-generation cephalosporin and carbapenem antibiotics.
• Antibacterial Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new antimicrobial entities.
• Process Chemistry: Used in the optimization and scale-up of API (Active Pharmaceutical Ingredient) manufacturing processes.
• Academic Research: A valuable compound for biochemical and pharmacological studies focused on β-lactamase inhibition and bacterial resistance mechanisms.
• Custom Synthesis: Starting material for the preparation of specialized derivatives and analogs for proprietary drug discovery programs.

Basic Information

Product Name	4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylicacid,6-(1-Hydroxyethyl)-3-Methyl-7-Oxo-,(5Alpha,6Bta)-(9Ci)
CAS No.	793618-48-1
Molecular Formula	C10H13NO4S
Molecular Weight	243.28 g/mol
Synonyms	(5α,6β)-6-(1-Hydroxyethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid; 6β-(1-Hydroxyethyl)-3α-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2α-carboxylic Acid; Penicillanic Acid Derivative; β-Lactam Intermediate; 793618-48-1; 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-methyl-7-oxo-, (5α,6β)-; 9CI
EINECS	Contact for details

Quality Control

Our 4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylicacid,6-(1-Hydroxyethyl)-3-Methyl-7-Oxo-,(5Alpha,6Bta)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and pharmaceutical-grade standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.