Description

Abagovomab is a monoclonal anti-idiotypic antibody designed to mimic the CA-125 antigen, a key biomarker in ovarian cancer. This compound is of significant interest in the field of oncology research and therapeutic development for its potential in active immunotherapy. It is primarily utilized by pharmaceutical R&D teams, biotech companies, and clinical research organizations focused on advancing cancer treatment strategies. The product is supplied under stringent quality controls to ensure consistency for critical research and development applications.

Application

• Oncology Research: A key reagent for studying the immune response to the CA-125 tumor-associated antigen.
• Therapeutic Vaccine Development: Serves as an active immunotherapeutic agent in clinical trials for ovarian cancer.
• Immunoassay Development: Used in the development and validation of diagnostic assays targeting CA-125.
• Preclinical Studies: Essential for in vitro and in vivo models to evaluate efficacy and mechanism of action.
• Biopharmaceutical Manufacturing: Acts as a reference standard or an intermediate in the production of immunotherapies.
• Academic Research: Supports fundamental studies in tumor immunology and antibody engineering.

Basic Information

Product Name	Abagovomab
CAS No.	792921-10-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Anti-CA-125 Anti-Idiotypic Antibody; ACA125; Monoclonal Antibody ACA125; Ovarex; (Ab-2) Monoclonal Antibody; Anti-Idiotype Antibody to CA125; CA-125 Mimic Antibody
EINECS	Contact for details

Quality Control

Our Abagovomab is produced and tested under a rigorous quality management system. Each batch is subjected to comprehensive analytical testing, including purity assessment by HPLC, identity confirmation, and biological activity assays to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under controlled, dry conditions to prevent degradation. For optimal results, allow the vial to equilibrate to room temperature before opening.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Protein Content (UV)	≥ 90.0%
Endotoxin Level (LAL)	< 10.0 EU/mg
Biological Activity (Binding Assay)	Conforms to reference
Solubility	Soluble in PBS or suitable aqueous buffer
Residual Moisture (KF)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.