Description

Bicyclo[2.2.1]Heptane-2-Carbonitrile, 5-Amino-2-Methyl-, (Exo,Exo)- (9Ci) is a high-purity, stereochemically defined norbornane derivative that serves as a critical chiral building block in advanced organic synthesis. Its rigid bicyclic framework and strategically positioned amino and cyano functional groups make it an invaluable precursor for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for applications in asymmetric catalysis, medicinal chemistry, and the development of novel agrochemicals and materials science intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalysis Ligand Precursor: Used to develop and synthesize novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Serves as a building block for creating new, stereospecific herbicides, fungicides, and plant growth regulators.
• Advanced Material Science: Employed in the research of specialty polymers, liquid crystals, and other functional materials requiring rigid, chiral cores.
• Academic & Industrial R&D: A valuable tool compound for methodological development in organic chemistry and exploring new reaction pathways.
• Peptidomimetics & Bioisosteres: The constrained norbornane skeleton is used to mimic peptide turns and create metabolically stable bioisosteres in drug design.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Carbonitrile, 5-Amino-2-Methyl-, (Exo,Exo)- (9Ci)
CAS No.	792870-18-9
Molecular Formula	C9H14N2
Molecular Weight	150.22 g/mol
Synonyms	(1R,2S,4R)-5-Amino-2-methylbicyclo[2.2.1]heptane-2-carbonitrile; (Exo,Exo)-5-Amino-2-methylbicyclo[2.2.1]heptane-2-carbonitrile; 5-Amino-2-methyl-2-norbornanecarbonitrile (exo,exo isomer); 2-Norbornanecarbonitrile, 5-amino-2-methyl-, (1R,2S,4R)-rel-; Amino-methyl norbornane carbonitrile; Chiral norbornane nitrile; Bicyclo[2.2.1]heptane-2-carbonitrile, 5-amino-2-methyl-, (1R,2S,4R)-
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-2-Carbonitrile, 5-Amino-2-Methyl-, (Exo,Exo)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, isomeric purity, and chemical assay. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (Chiral HPLC)	≥ 99.0% (Exo,Exo)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.