Description

(S)-1-(Tetrahydro-2H-Pyran-4-Yl)Pyrrolidin-3-Amine is a high-purity chiral amine building block of significant importance in modern pharmaceutical research and development. Its core value lies in its rigid, bicyclic scaffold and stereogenic center, which are crucial for creating selective and potent bioactive molecules. This compound is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of central nervous system (CNS) active drugs and other therapeutic agents.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study biological pathways and protein function.
• Agrochemical Research: Employed in the discovery of new, selective pesticides and herbicides that require specific stereochemistry for activity.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.
• Academic Research: Utilized in universities and research institutes for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	(S)-1-(Tetrahydro-2H-Pyran-4-Yl)Pyrrolidin-3-Amine
CAS No.	791758-82-2
Molecular Formula	C9H18N2O
Molecular Weight	170.25 g/mol
Synonyms	(3S)-1-(Oxan-4-yl)pyrrolidin-3-amine; (S)-3-Amino-1-(tetrahydro-2H-pyran-4-yl)pyrrolidine; (S)-1-(Tetrahydro-2H-pyran-4-yl)-3-pyrrolidinamine; Pyrrolidin-3-amine, 1-(tetrahydro-2H-pyran-4-yl)-, (3S)-; (S)-1-(THP-4-yl)pyrrolidin-3-amine; (S)-1-(Tetrahydropyran-4-yl)pyrrolidin-3-amine
EINECS	Contact for details

Quality Control

Our (S)-1-(Tetrahydro-2H-Pyran-4-Yl)Pyrrolidin-3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.