Description

(tert-Butoxy)Carbonyl D-2-Fluoro-4-Chlorophe is a high-purity, chiral building block of significant importance in advanced organic synthesis. Its core value lies in providing a protected, enantiomerically pure intermediate that enables the precise construction of complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-fidelity chiral precursors for developing active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and anti-infective drugs.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce the D-2-fluoro-4-chlorophenylalanine moiety.
• Agrochemical Research: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Proteomics & Biochemistry: Employed in the synthesis of isotopically labeled or modified peptides and proteins for metabolic studies and biochemical assays.
• Ligand & Catalyst Development: Utilized in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Material Science: A precursor for specialty polymers and advanced materials requiring specific chiral architectures.

Basic Information

Product Name	(tert-Butoxy)Carbonyl D-2-Fluoro-4-Chlorophe
CAS No.	791625-58-6
Molecular Formula	C14H17FClNO4
Molecular Weight	317.74 g/mol
Synonyms	Boc-D-2-Fluoro-4-chlorophenylalanine; N-Boc-D-2-Fluoro-4-chlorophenylalanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(2-fluoro-4-chlorophenyl)propanoic acid; Boc-D-F(2)Cl(4)-Phe-OH; D-2-Fluoro-4-chloro-Boc-Phe; N-(tert-Butoxycarbonyl)-D-2-fluoro-4-chlorophenylalanine; Boc-D-2-F-4-Cl-Phe; tert-Butyl (R)-2-amino-3-(2-fluoro-4-chlorophenyl)propanoate, N-Boc derivative
EINECS	Contact for details

Quality Control

Our (tert-Butoxy)Carbonyl D-2-Fluoro-4-Chlorophe is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.