Description

2-Propanamine, 1,1,1-Trifluoro-3-Nitro- is a specialized fluorinated nitroamine building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoromethyl and nitro functional groups, which are critical for modulating the physicochemical properties of target molecules, such as lipophilicity, metabolic stability, and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Fluorinated Compound Library: Serves as a valuable precursor for building diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials that require fluorinated components for specific thermal or chemical resistance properties.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes for constructing complex molecules containing both amine and nitro functionalities.

Basic Information

Product Name	2-Propanamine, 1,1,1-Trifluoro-3-Nitro-
CAS No.	791547-72-3
Molecular Formula	C₃H₅F₃N₂O₂
Molecular Weight	158.08 g/mol
Synonyms	1,1,1-Trifluoro-3-nitro-2-propanamine; 3-Amino-1,1,1-trifluoro-2-nitropropane; 2-Propanamine, 1,1,1-trifluoro-3-nitro-; 1,1,1-Trifluoro-3-nitropropan-2-amine; 3-Nitro-1,1,1-trifluoropropan-2-amine; TFNPA; Trifluoronitropropylamine
EINECS	Contact for details

Quality Control

Our production of 2-Propanamine, 1,1,1-Trifluoro-3-Nitro- adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.