Description

(tert-Butoxy)Carbonyl S-(γ)-Phe is a protected amino acid derivative, specifically a γ-substituted phenylalanine analog, with the CAS number 790223-54-0. This compound is a crucial high-purity building block for advanced organic synthesis, particularly in the development of novel peptides and peptidomimetics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic peptides and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate modified phenylalanine residues with a protected γ-position.
• Chemical Biology Research: Employed in the synthesis of activity-based probes and labeled peptides for studying enzyme mechanisms and protein-protein interactions.
• Ligand Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and medicinal chemistry.
• Academic & Institutional Research: Utilized in universities and research institutes for exploring novel amino acid chemistry and structure-activity relationships (SAR).

Basic Information

Item	Detail
Product Name	(tert-Butoxy)Carbonyl S-(γ)-Phe
CAS No.	790223-54-0
Molecular Formula	C14H19NO4
Molecular Weight	265.31 g/mol
Synonyms	Boc-S-(γ)-Phe; Boc-γ-Phe; N-(tert-Butoxycarbonyl)-S-(γ)-Phenylalanine; (S)-3-(tert-Butoxycarbonylamino)-3-phenylpropanoic Acid; (S)-3-((tert-Butoxycarbonyl)amino)-3-phenylpropanoic Acid; (S)-3-(Boc-amino)-3-phenylpropionic Acid; γ-(Boc-amino)-L-phenylalanine derivative; 790223-54-0
EINECS	Contact for details

Quality Control

Our (tert-Butoxy)Carbonyl S-(γ)-Phe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric excess, meeting the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.