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α-D-Arabinofuranose, 3,5-Dideoxy-3-Fluoro-2-o-(Phenylmethyl)- (9Ci) CAS NO 786709-91-9


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CAS No.:786709-91-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

α-D-Arabinofuranose, 3,5-Dideoxy-3-Fluoro-2-o-(Phenylmethyl)- (9Ci) CAS NO 786709-91-9 is a specialized fluorinated carbohydrate derivative, serving as a critical synthetic intermediate in advanced organic and medicinal chemistry. Its value lies in its unique structure, which incorporates a fluorine atom and a benzyl protecting group, making it a versatile building block for constructing complex bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other fine chemicals where precise stereochemistry and fluorination are required.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
  • Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to investigate the role of fluorinated sugars in drug metabolism and bioavailability.
  • Glycochemistry Research: Serves as a protected, fluorinated arabinofuranose precursor for the study of carbohydrate-protein interactions and enzyme inhibitors.
  • Probe and Diagnostic Development: Potential use in creating molecular probes, such as Positron Emission Tomography (PET) tracers, utilizing the fluorine-18 isotope.
  • Process Chemistry: Employed in route scouting and optimization for the scalable production of fluorinated active pharmaceutical ingredients (APIs).
  • Academic Research: A valuable reagent for synthetic organic chemists exploring new methodologies in glycosylation and fluorination reactions.

Basic Information

Product Name α-D-Arabinofuranose, 3,5-Dideoxy-3-Fluoro-2-o-(Phenylmethyl)- (9Ci)
CAS No. 786709-91-9
Molecular Formula C12H15FO4
Molecular Weight 242.24 g/mol
Synonyms 2-O-Benzyl-3,5-dideoxy-3-fluoro-α-D-arabinofuranose; 3,5-Dideoxy-3-fluoro-2-O-(phenylmethyl)-α-D-arabinofuranose; α-D-Arabinofuranose, 3,5-dideoxy-3-fluoro-2-O-(phenylmethyl)-; 2-O-Benzyl-3-deoxy-3-fluoro-α-D-arabinofuranose (common naming variant); Benzyl 3-deoxy-3-fluoro-α-D-arabinofuranoside; Fluorinated arabinose derivative; CAS 786709-91-9
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Quality Control

Every batch of α-D-Arabinofuranose, 3,5-Dideoxy-3-Fluoro-2-o-(Phenylmethyl)- (9Ci) is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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