Description

(9H-Fluoren-9-Yl)Methyl 3-Iodopropylcarbamate is a specialized organic building block and reagent designed for advanced synthetic chemistry. This compound is valued for its unique molecular architecture, which incorporates both a fluorenylmethyloxycarbonyl (Fmoc)-like protecting group and a reactive iodoalkyl chain. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Peptide and Protein Chemistry: Serves as a key reagent for the introduction of functionalized side chains or as a precursor for specialized protecting groups in solid-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in constructing molecular scaffolds with specific iodine-containing motifs for further cross-coupling reactions.
• Bioconjugation: Acts as a linker or functional handle for attaching fluorescent probes, drugs, or other payloads to biomolecules like proteins or antibodies.
• Material Science Research: Employed in the synthesis of functional polymers or dendrimers where precise placement of iodine atoms is required for subsequent modification or property tuning.
• Chemical Biology Probes: Useful in creating activity-based probes or affinity labels to study enzyme function and protein interactions.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methyl 3-Iodopropylcarbamate
CAS No.	786704-29-8
Molecular Formula	C18H18INO2
Molecular Weight	407.25 g/mol
Synonyms	3-Iodopropyl (9H-fluoren-9-yl)methyl carbamate; Fmoc-3-iodopropylamine derivative; N-(3-Iodopropyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]amine; 9-Fluorenylmethyl N-(3-iodopropyl)carbamate; Carbamic acid, N-(3-iodopropyl)-, 9H-fluoren-9-ylmethyl ester; Fmoc-3-iodopropyl carbamate
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl 3-Iodopropylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, reporting key parameters such as assay (by HPLC), related substances, and residual solvents. We support research and development with material that meets the stringent requirements for pharmaceutical intermediates and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.