Description

Proline, 5-(4-Methylphenyl)- (9Ci) is a specialized proline derivative characterized by the presence of a 4-methylphenyl substituent. This structural modification makes it a valuable non-natural amino acid building block for advanced research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers. The compound is offered with a CAS number of 784984-08-3.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for peptidomimetics and small molecule drugs.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce structural constraints or modulate the physicochemical properties of peptide sequences.
• Chemical Biology Research: Acts as a probe or building block in the study of enzyme-substrate interactions, protein folding, and receptor-ligand binding due to its modified proline scaffold.
• Agrochemical Development: Employed in the synthesis of advanced crop protection agents where specific stereochemistry and aromatic functionality are required.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers and functional materials.

Basic Information

Product Name	Proline, 5-(4-Methylphenyl)- (9Ci)
CAS No.	784984-08-3
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	5-(p-Tolyl)-L-proline; (S)-5-(4-Methylphenyl)pyrrolidine-2-carboxylic acid; 5-(4-Methylphenyl)proline; 5-(p-Methylphenyl)proline; L-5-(4-Methylphenyl)proline; 5-(4-Methylphenyl)-2-pyrrolidinecarboxylic acid; 784984-08-3; 5-(4-Methylphenyl)-L-proline
EINECS	Contact for details

Quality Control

Our Proline, 5-(4-Methylphenyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.