Description

2H-Azepin-2-One,3-Aminohexahydro-6-(3-Methylphenyl)-,(3R)-(9Ci) CAS NO 784156-08-7 is a high-purity, stereochemically defined azepinone derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in its complex molecular architecture, which provides a versatile scaffold for constructing pharmacologically active molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly those focused on developing novel therapeutic agents and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and oncology drug discovery.
• Asymmetric Synthesis: Used as a sophisticated building block in stereoselective synthesis to introduce the azepinone core into complex molecular targets.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for candidate drugs.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic and organonitrogen chemistry.
• Fine Chemical Production: Incorporated into the synthesis of specialty chemicals, catalysts, and advanced materials requiring specific chiral motifs.

Basic Information

Product Name	2H-Azepin-2-One,3-Aminohexahydro-6-(3-Methylphenyl)-,(3R)-(9Ci)
CAS No.	784156-08-7
Molecular Formula	C13H18N2O
Molecular Weight	218.30 g/mol
Synonyms	(3R)-3-Aminohexahydro-6-(3-methylphenyl)-2H-azepin-2-one; 3-Amino-6-(3-methylphenyl)hexahydro-2H-azepin-2-one, (3R)-; (3R)-3-Amino-6-(m-tolyl)hexahydro-2H-azepin-2-one; 784156-08-7; (R)-3-Amino-6-(3-methylphenyl)perhydroazepin-2-one; Azepin-2-one, 3-aminohexahydro-6-(3-methylphenyl)-, (3R)-; A chiral azepinone derivative
EINECS	Contact for details

Quality Control

Our 2H-Azepin-2-One,3-Aminohexahydro-6-(3-Methylphenyl)-,(3R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.