Description

1-Piperidinecarboxylic Acid, 4-(2-Amino-2-Oxoethyl)-, 1,1-Dimethylethyl Ester is a high-purity, protected amino acid derivative of significant value in advanced organic synthesis. This compound serves as a critical building block for the development of complex molecules, offering a versatile scaffold for medicinal chemistry and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for constructing novel active pharmaceutical ingredients (APIs) and peptide mimetics.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptidomimetic Chemistry: Used to introduce constrained piperidine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Serves as a precursor for labeled compounds or affinity tags used in target identification and validation studies.
• Agrochemical Research: Employed in the development of new active ingredients with specific biological activity.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploratory synthesis projects.
• Custom Synthesis: Acts as a starting material for bespoke chemical entities produced under cGMP or research-grade conditions.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-(2-Amino-2-Oxoethyl)-, 1,1-Dimethylethyl Ester
CAS No.	782493-57-6
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	tert-Butyl 4-(2-amino-2-oxoethyl)piperidine-1-carboxylate; 1-Boc-4-(2-amino-2-oxoethyl)piperidine; 4-(Aminocarbonylmethyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; Boc-4-(2-amino-2-oxoethyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(2-amino-2-oxoethyl)piperidine; N-Boc-4-(carbamoylmethyl)piperidine; 4-(Carbamoylmethyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your critical research and development work. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.