Description

2-Naphthalenamine,6-Fluoro-1,2,3,4-Tetrahydro-,(S)-(9Ci) is a chiral, fluorinated tetrahydro-naphthalene amine derivative, serving as a sophisticated pharmaceutical intermediate and building block in organic synthesis. Its value lies in the precise stereochemistry and the introduction of a fluorine atom, which are critical for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This high-purity compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances bioactivity and environmental stability.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in stereoselective synthetic transformations.
• Chemical Research: Serves as a valuable scaffold in medicinal chemistry for library synthesis and lead optimization studies.
• Fluorine Chemistry Studies: A model compound for investigating the effects of fluorination on aromatic and alicyclic amine systems.

Basic Information

Product Name	2-Naphthalenamine,6-Fluoro-1,2,3,4-Tetrahydro-,(S)-(9Ci)
CAS No.	782427-32-1
Molecular Formula	C₁₀H₁₂FN
Molecular Weight	165.21 g/mol
Synonyms	(S)-6-Fluoro-1,2,3,4-tetrahydronaphthalen-2-amine; (2S)-6-Fluoro-1,2,3,4-tetrahydronaphthalen-2-amine; 6-Fluoro-1,2,3,4-tetrahydronaphthalen-2-amine, (S)-; (S)-6-Fluoro-1,2,3,4-tetrahydro-2-naphthylamine; (S)-6-Fluoro-2-amino-1,2,3,4-tetrahydronaphthalene; 782427-32-1; (S)-6-Fluoro-2-tetralinamine
EINECS	Contact for details

Quality Control

Our production of 2-Naphthalenamine,6-Fluoro-1,2,3,4-Tetrahydro-,(S)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral HPLC to confirm enantiomeric excess. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.