Description

1,2-Cyclopropanedicarboxylicacid,1-(Acetylamino)-,(1R,2R)-Rel-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid cyclopropane scaffold and functional groups make it a valuable intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of novel, stereospecific pesticides and herbicides where the defined spatial orientation of the molecule is critical for biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of specialized chiral ligands and organocatalysts.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Institutional Research: A valuable tool for methodological studies in organic synthesis, particularly in cyclopropane chemistry and stereoselective transformations.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylicacid,1-(Acetylamino)-,(1R,2R)-Rel-(9Ci)
CAS No.	781608-33-1
Molecular Formula	C8H11NO5
Molecular Weight	201.18 g/mol
Synonyms	(1R,2R)-1-Acetamidocyclopropane-1,2-dicarboxylic Acid; (1R,2R)-1-(Acetylamino)cyclopropane-1,2-dicarboxylic Acid; rel-(1R,2R)-1-Acetamidocyclopropane-1,2-dicarboxylic Acid; (1R,2R)-1-Acetamido-1,2-cyclopropanedicarboxylic Acid; ACPD derivative; Chiral ACPD; Cyclopropane amino acid derivative
EINECS	Contact for details

Quality Control

Our production of 1,2-Cyclopropanedicarboxylicacid,1-(Acetylamino)-,(1R,2R)-Rel-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity verification. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.