Description

Pentanoic Acid, 5-Amino-2-Fluoro-4-Oxo-, Methyl Ester is a high-purity, fluorinated amino acid derivative with significant synthetic utility. This compound serves as a versatile and critical building block in advanced organic synthesis, particularly for introducing specific functional groups into complex molecular architectures. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including potential protease inhibitors and kinase modulators.
• Peptidomimetics Research: Used to incorporate fluorinated and keto-amino acid motifs into peptide analogs to enhance metabolic stability and binding affinity.
• Agrochemical Synthesis: Serves as a building block for developing novel, fluorinated herbicides or plant growth regulators with improved efficacy.
• Material Science: Potential monomer or modifier in the creation of specialized polymers with unique surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes (ABPs) or labeled compounds for studying enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific fluorinated and functionalized side chains.

Basic Information

Product Name	Pentanoic Acid, 5-Amino-2-Fluoro-4-Oxo-, Methyl Ester
CAS No.	780722-28-3
Molecular Formula	C7H10FNO4
Molecular Weight	191.16 g/mol
Synonyms	Methyl 5-amino-2-fluoro-4-oxopentanoate; 5-Amino-2-fluoro-4-oxopentanoic acid methyl ester; 2-Fluoro-4-oxo-5-aminopentanoic acid methyl ester; 5-Azaniumyl-2-fluoro-4-oxopentanoate methyl ester; Methyl 5-azaniumyl-2-fluoro-4-oxopentanoate; (S)-Methyl 5-amino-2-fluoro-4-oxopentanoate (for enantiopure form); 5-Amino-2-fluoro-4-oxo-pentanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Pentanoic Acid, 5-Amino-2-Fluoro-4-Oxo-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.