Description

2-Benzyloxy-5-Fluorophenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to synthesize complex fluorinated aromatic structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorophenyl moiety enhances biological activity and stability.
• Ligand & Catalyst Development: Serves as a starting material for constructing sophisticated ligands used in catalysis and molecular recognition.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, via polymerization or small-molecule synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes for imaging and studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	2-Benzyloxy-5-Fluorophenylboronic Acid
CAS No.	779331-47-4
Molecular Formula	C₁₃H₁₂BFO₃
Molecular Weight	246.05 g/mol
Synonyms	(2-(Benzyloxy)-5-fluorophenyl)boronic acid; 5-Fluoro-2-(phenylmethoxy)benzeneboronic acid; 2-Benzyloxy-5-fluorobenzeneboronic acid; (5-Fluoro-2-(benzyloxy)phenyl)boronic acid; B-(2-Benzyloxy-5-fluorophenyl)boronic acid; 779331-47-4; 2-Benzyloxy-5-fluorophenyl-Boronic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Benzyloxy-5-Fluorophenylboronic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request, supporting compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and reactivity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.